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Benzylamine → N-(4-[(7-Methoxyheptyl)oxy]butanoyl)-L-isoleucine, ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzylamine | HCID 7504 | — |
| 反応物 | L-Isoleucine, ethyl ester | HCID 6602175 | — |
| 反応物 | 4-[(7-Methoxyheptyl)oxy]butanoyl chloride | HCID 15383030 | — |
| 反応物 | 12-Methoxydodecanoyl chloride | HCID 19611759 | — |
| 反応物 | L-isoleucine ethyl ester trifluoroacetate | HCID 88304807 | — |
| 生成物 | N-(4-[(7-Methoxyheptyl)oxy]butanoyl)-L-isoleucine, ethyl ester | HCID 131721076 | — |
反応手順
The title compound is prepared by the method of Example 14 using L-isoleucine ethyl ester trifluoroacetate [the title product of Example 44] as a reactant instead of benzylamine, and using an equivalent amount of 4-[(7-methoxyheptyl)oxy]butanoyl chloride [the title product of Example 100] instead of 12-methoxy-1-docecanoyl chloride [the title product of Example 11].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05952377 |
| 出典データセット | uspto-grants-1999_09 |
| ORD ID | ord-e061361843354fe9a03f11b4cceec927 |
| 出典メモ | uspto-grants-1999_09 |