HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Benzisothiazol-3(2H)-one, 2-(4-bromobutyl)-5-chloro-, 1,1-dioxide → HCID 18695973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Benzisothiazol-3(2H)-one, 2-(4-bromobutyl)-5-chloro-, 1,1-dioxide | HCID 13365980 | — |
| Reactant | 1-(1-methylethyl)-3-(4-piperidinyl)-2H-benzimidazol-2-one | HCID 18695994 | — |
| Product | HCID 18695973 | HCID 18695973 | — |
Reaction Steps
From 4-(3-isopropyl-2-oxo-1-benzimidazolinyl)piperidine and 1,1-dioxido-2-(4-bromobutyl)-5-chloro-1,2-benzisothiazol-3(2H)-one (prepared as shown in Example 22) using the procedures described in Example 1 there was obtained a white solid upon formation of the HCl salt (from methanol and diethyl ether), melting point 229-234° C. Analysis calculated for C26H31ClN4O4S.HCl.0.4 H2O: C, 54.33; H, 5.75; N, 9.75; found: C, 54.35; H, 5.60; N, 9.70. The NMR was consistent with the structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05952351 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-580cfdda125940fdaac54b77506c85c7 |
| Source note | uspto-grants-1999_09 |