Ethyl 6-bromohexanoate → HCID 22000304, compound

HRID 618496Notes

Reaction equation

HRID 618496 reaction equation
[C:1]12([C:11]3[CH:20]=[C:19]4[C:14]([CH:15]=[CH:16][C:17]([C:21]5[CH:32]=[CH:31][C:24]([C:25]([O:27][CH2:28][CH:29]=[CH2:30])=[O:26])=[CH:23][CH:22]=5)=[CH:18]4)=[CH:13][C:12]=3O)[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.BrC[CH2:36][CH2:37][CH2:38][CH2:39][C:40]([O:42]CC)=O>>[C:1]12([C:11]3[CH:20]=[C:19]4[C:14]([CH:15]=[CH:16][C:17]([C:21]5[CH:22]=[CH:23][C:24]([C:25]([O:27][CH2:28][CH:29]=[CH2:30])=[O:26])=[CH:31][CH:32]=5)=[C:18]4[O:42][CH2:40][CH2:39][CH2:38][CH2:37][CH3:36])=[CH:13][C:12]=3[C:25]([O:27][CH2:28][CH3:29])=[O:26])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Participants

3

Reactant 2

HCID 117544Ethyl 6-bromohexanoateHCID 22000346HCID 22000346, compound

Product 1

HCID 22000304HCID 22000304, compoundYield 108.9%

Procedure

Following the procedure of Example 12(a), but reacting 3 g (6.8 mmol) of allyl 4-[7-(1-adamantyl)-6-hydroxy-2-naphthyl]benzoate with 2.3 g (10.2 mmol) of ethyl 6-bromohexanoate, 2.15 g (55%) of the expected compound were obtained, which compound had a melting point of 116°-7° C.

Sources & evidence

ORD record
ord-74873927c49a4933aa4d37b4fa7f5df4
Source dataset
uspto-grants-1999_09
Patent number
US05952382

Reaction notes

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