Sodium Hydroxide → HCID 178444212, compound

Participants

Reaction Steps

1.70 g (81%) R,S-((3-(12-cyclohexyldodecylthio)-2-decyloxy)-propoxy)-hydroxy-phosphinyl-formic acid methyl ester (example 12.28) was obtained analogously to example 1 as a colourless oil from 0.55 g (3.10 mmol) 16 and 1.50 g (3.10 mmol) R,S-2-decyloxy-3-(12-cyclohexyldodecylthio)-1-propanol. Saponification of 1.50 g of this ester with sodium hydroxide solution (example 1) yielded 1.10 g (71%) 8 with a melting point of 105-107° C.

Provenance & Evidence