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HRID618638

反应详情

EQUATION

反应方程式

HRID 618638 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])c1ccc(F)cc1F
HCID67967

1-Nitro-2,4-difluorobenzene

C6H3F2NO2

结构：CCOP(=O)(CN)OCC
HCID1596920

diethyl aminomethylphosphonate

C5H14NO3P

PRODUCTS

生成物

1
结构：CCOP(=O)(CNc1cc(F)ccc1[N+](=O)[O-])OCC
HCID17800777

未命名化合物

收率 75.6%

PROCEDURE

实验过程

1.1 g of 2,4-difluoronitrobenzene is heated with 2.8 g of aminomethanephosphonic acid diethyl ester for 2 hours to 40° C. Then, it is chromatographed on silica gel with methylene chloride:ethanol=10:1. 1.6 g of N-(2-nitro-5-fluorophenyl)aminomethanephosphonic acid diethyl ester is obtained.

WORKUP

后处理

  1. customThen, it is chromatographed on silica gel with methylene chloride