HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonitrile, 4-chloro-3-nitro- → HCID 86752536, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonitrile, 4-chloro-3-nitro- | HCID 13655 | — |
| Reactant | Phosphonic acid, (1-aminoethyl)-, diethyl ester | HCID 5149858 | — |
| Product | HCID 86752536 | HCID 86752536 | 80% |
Reaction Steps
2.77 g (15.24 mmol) of 4-chloro-3-nitrobenzonitrile is stirred with 10.5 g (38 mmol) of 1-aminoethanephosphonic acid diethyl ester for 16 hours at 30° C. The reaction mixture is then chromatographed on silica gel with methylene chloride:ethanol=95:5 as eluant. 3.86 g (80% of theory) of 1-[N-(2-nitro-4-cyanophenyl)amino]ethanephosphonic acid diethyl ester is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05955461 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-bc3c91ee93824eadbff5ea64fef8e700 |
| Source note | uspto-grants-1999_09 |