HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-2-(4-vinylphenyl)propanoic acid → 2-(4-Ethylphenyl)-2-methylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-2-(4-vinylphenyl)propanoic acid | HCID 66834551 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(4-Ethylphenyl)-2-methylpropanoic acid | HCID 58128446 | 96.4% |
Reaction Steps
2-(4-Vinylphenyl)-2-methylpropanoic acid (58 g) was dissolved in ethanol, and then stirred for 3 hrs under atmospheric hydrogen pressure in the presence of 10% palladium carbon (5.8 g). The catalyst was removed by filtration, and the filtrate was concentrated to obtain a crude product, which was then suspended and washed with hexane to give the title compound (56.5 g, 94.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440922B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-b5b10f936bab44d9be593fd78d91204d |
| Source note | uspto-grants-2016_09 |