Potassium Hydroxide → HCID 67597722, compound

HRID 618809Notes

Reaction equation

[CH2:1]([C:3]1([CH2:25][CH3:26])[CH2:12][CH:11]([CH2:13][CH2:14][S:15]([NH:18][CH2:19][C:20]([O:22]C)=[O:21])(=[O:17])=[O:16])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH3:24])[CH:9]=2)[O:4]1)[CH3:2].[OH-].[K+]>>[CH2:25]([C:3]1([CH2:1][CH3:2])[CH2:12][CH:11]([CH2:13][CH2:14][S:15]([NH:18][CH2:19][C:20]([OH:22])=[O:21])(=[O:17])=[O:16])[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH3:24])[CH:9]=2)[O:4]1)[CH3:26]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 86754515HCID 86754515, compound

Product 1

HCID 67597722HCID 67597722, compoundYield 92.6%

Procedure

By hydrolysis of 1.0 g (2.6 mmol) of methyl [(2,2-diethyl-6-methylchroman-4-yl)ethylsulfonylamino]acetate with 0.44 g (7.8 mmol) of KOH analogously to Example 2a, 0.89 g of [(2,2-diethyl-6-methylchroman-4-yl)ethylsulfonylamino]acetic acid is obtained.

Sources & evidence

ORD record: ord-e1aa90a6e7ea43d7a7c3710641992e05
Source dataset: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05955607

Reaction notes

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