HCID 21844914, compound → HCID 21844912, compound

HRID 618946Notes

Reaction equation

HRID 618946 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:18]([C:20]2[CH:25]=[C:24]([C:26]([NH:28][CH2:29][CH:30]([OH:33])[CH2:31][OH:32])=[O:27])[CH:23]=[C:22]([N+:34]([O-])=O)[CH:21]=2)=[O:19])[CH:7]=[C:8]([C:10]([NH:12][CH2:13][CH:14]([OH:17])[CH2:15][OH:16])=[O:11])[CH:9]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:5]=[C:6]([CH:18]([C:20]2[CH:25]=[C:24]([C:26]([NH:28][CH2:29][CH:30]([OH:33])[CH2:31][OH:32])=[O:27])[CH:23]=[C:22]([NH2:34])[CH:21]=2)[OH:19])[CH:7]=[C:8]([C:10]([NH:12][CH2:13][CH:14]([OH:17])[CH2:15][OH:16])=[O:11])[CH:9]=1

Participants

4

Reactant 1

HCID 21844914HCID 21844914, compound

Product 1

HCID 21844912HCID 21844912, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Di[3-nitro-5-(2,3-dihydroxypropylaminocarbonyl)phenyl]ketone (0.70 g, 1.4 mmol) was dissolved in methanol (40 ml) and was hydrogenated at 60 psi using a Pd/C catalyst (10%, 0.20 g). The catalyst was filtered off and the solvent was evaporated. Analysis by 1H NMR indicated complete conversion to the product. Yield: 0.62 g (100%).

Workup

  1. filtrationThe catalyst was filtered off
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-093b02e5b45244bfaa9ea1f669cb829a
Source dataset
uspto-grants-1999_09
Patent number
US05958375

Reaction notes

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