HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Tert-butylpropanedioic acid → 4-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Tert-butylpropanedioic acid | HCID 242752 | — |
| Reactant | 2-(6-Methoxypyridin-2-yl)-2-methylpropanoic acid | HCID 66834994 | — |
| Product | 4-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester | HCID 66834539 | — |
Reaction Steps
The title compound was synthesized from 2-(6-methoxy-pyridin-2-yl)-2-methyl-propionic acid and mono-tert-butyl malonic acid according to the method used for the synthesis of Compound PR4. The resultant was used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09440922B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-60e0ae8c3d4c4b138837dde5fb727092 |
| Source note | uspto-grants-2016_09 |