反应详情

A solution (35 ml) of 4-N HCl/dioxane was added to 2.65 (10.0 mmols) of N-tert-butoxycarbonyl-(R)-α-methylthiomethylbenzylamine, and the mixture was stirred at room temperature for 1 hour. The reaction solution was concentrated under reduced pressure, and the residue was concentrated with the addition of 30 ml of ether to obtain (R)-α-methylthiomethylbenzylamine hydrochloride in a quantitative yield.

1. concentrationThe reaction solution was concentrated under reduced pressure
2. concentrationthe residue was concentrated with the addition of 30 ml of ether