反应详情

温度

5 °C

A solution of 10.6 ml of phenylcyclohexane in 100 ml of methylene chloride was added at 5° C. within 30 minutes to 13.8 ml of chlorosulfonic acid. The mixture was stirred at 5° C. for 1 hour, poured into 400 ml of a 20% ammonium chloride solution and extracted twice with 300 ml of methylene chloride each time. The organic phases were combined, dried with magnesium sulphate and the solvent was removed on a rotary evaporator. 13.6 g of 4-cyclohexyl-benzenesulfonyl chloride separated as a reddish oil, which was used without further purification.

1. extractionextracted twice with 300 ml of methylene chloride each time
2. dry with materialdried with magnesium sulphate
3. customthe solvent was removed on a rotary evaporator
4. custom13.6 g of 4-cyclohexyl-benzenesulfonyl chloride separated as a reddish oil, which
5. customwas used without further purification