Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 2-Bromo-1-[3-(trifluoromethyl)phenyl]ethan-1-one | HCID 2778386 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 21845597 | HCID 21845597 | — |
Reaction Steps
A solution of 8.1 g of 2-bromo-1-(3-trifluoromethyl-phenyl)-ethanone in 70 ml of methanol was treated at room temperature with 3.2 g of thiourea and boiled for 1 hour. 4.1 g of 4-(3-trifluoromethyl-phenyl)-thiazol-2-ylamine hydrobromide separated as colorless crystals upon cooling to 0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05958910 |
|---|
| Source dataset | uspto-grants-1999_09 |
|---|
| ORD ID | ord-0178b6ea4e5b43b4a6143f810a2d9795 |
|---|
| Source note | uspto-grants-1999_09 |
|---|
