HRID619080

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID88031

2-Bromo-1-(3-(phenylmethoxy)phenyl)ethan-1-one

C15H13BrO2

HCID2723790

Thiourea

CH4N2S

PRODUCTS

生成物

HCID16495478

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

CONDITIONS

反应条件

温度: 0 °C

PROCEDURE

实验过程

A solution of 22.5 g of 2-bromo-1-(3-benzyloxy-phenyl)-ethanone in 150 ml of methanol was treated at room temperature with 7.8 g of thiourea and boiled for 1 hour. 16.1 g of 4-(3-benzyloxy-phenyl)-thiazol-2-ylamine hydrobromide separated as colorless crystals upon cooling to 0° C.

WORKUP

后处理

custom16.1 g of 4-(3-benzyloxy-phenyl)-thiazol-2-ylamine hydrobromide separated as colorless crystals