化工社化工社 化学情報印刷レポート · 研究参考用
2-((1,1-Dimethylethoxy)methyl)oxirane → 1-[4-(1,1-Dioxo-thiomorpholin-4-yl)-phenoxy]-3-(t-butyloxy)propan-2-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-((1,1-Dimethylethoxy)methyl)oxirane | HCID 24314 | — |
| 反応物 | 4-(4-Hydroxyphenyl)thiomorpholine 1,1-Dioxide | HCID 21845223 | — |
| 触媒 | Phosphonium, ethyltriphenyl-, bromide (1:1) | HCID 73727 | — |
| 生成物 | 1-[4-(1,1-Dioxo-thiomorpholin-4-yl)-phenoxy]-3-(t-butyloxy)propan-2-ol | HCID 21845221 | 78.3% |
反応手順
4-(1,1-dioxo-thiomorpholin-4-yl)phenol (2.3 g, 10 mmol), t-butylglycidyl ether (1.56 g, 12 mmol) and ethyltriphenylphosphonium bromide (0.1 g) are reacted and purified as described for compound 102 to afford a light yellow liquid 2.8 g (78%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05958663 |
| 出典データセット | uspto-grants-1999_09 |
| ORD ID | ord-1f9c5ef8ab5448cfb6e3d1a81695b64d |
| 出典メモ | uspto-grants-1999_09 |