HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Hydroxyphenyl)thiomorpholine 1,1-Dioxide → 1-[4-(1,1-Dioxo-thiomorpholin-4-yl)-phenoxy]-3-(isooctyloxy)-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Hydroxyphenyl)thiomorpholine 1,1-Dioxide | HCID 21845223 | — |
| Reactant | Oxirane, 2-[[(6-methylheptyl)oxy]methyl]- | HCID 22571168 | — |
| Catalyst | Phosphonium, ethyltriphenyl-, bromide (1:1) | HCID 73727 | — |
| Product | 1-[4-(1,1-Dioxo-thiomorpholin-4-yl)-phenoxy]-3-(isooctyloxy)-propan-2-ol | HCID 21845231 | 69% |
Reaction Steps
4-(1,1-dioxo-thiomorpholin-4-yl)phenol (2.3 g, 10 mmol), isooctylglycidyl ether (1.9 g, 10 mmol) and ethyltriphenylphosphonium bromide (0.2 g) are reacted and purified as described for compound 102 to afford a light yellow liquid 2.85 g (69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05958663 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-9fab45436ced4ece97252426ec2e2c80 |
| Source note | uspto-grants-1999_09 |