HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 619292Generated: October 25, 2026
Ethyl Acetate → 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)butan-1,3-dione
https://huagongshe.com/reaction/619292
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)ethanone | HCID 21268052 | — |
| Product | 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)butan-1,3-dione | HCID 21846291 | — |
Reaction Steps
1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-ethanone (1.2 g) was dissolved in 20 mL of ethyl acetate, and sodium hydride (0.33 g, 60% oil dispersion) was added. The reaction mixture was heated to 80° C. overnight, quenched with water, and neutralized with carbon dioxide to give an oily product of 1-(2,3-dihydro-1,4-benzodioxin-5-yl)butan-1,3-dione (0.37 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05958934 |
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| Source dataset | uspto-grants-1999_09 |
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| ORD ID | ord-b3584252cc8a4342b691132d71b2298f |
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| Source note | uspto-grants-1999_09 |
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