反应详情

A solution of 4-nitrophenyl isothiocyanate (0.45 g, 2.52 mmol) in dioxane (25 mL) is slowly added, with magnetic stirring, to a solution of 4,4'-diaminodiphenyl methane (0.25 g, 1.26 mmol) in dioxane (10 mL). After 24 hours of stirring at room temperature, the solvent is removed by vacuum evaporation. The solid obtained is washed with n-hexane (3×25 mL) and isopropanol (3×10 mL). Next, the solid is dissolved in ethyl acetate (50 mL) and washed with water (3×25 mL). The organic phase is dried with sodium sulfate. The solvent is removed by vacuum evaporation. The titled compound is obtained as a yellow powder. mp: 115° C.

1. customthe solvent is removed by vacuum evaporation
2. customThe solid obtained
3. washis washed with n-hexane (3×25 mL) and isopropanol (3×10 mL)
4. dissolutionNext, the solid is dissolved in ethyl acetate (50 mL)
5. washwashed with water (3×25 mL)
6. dry with materialThe organic phase is dried with sodium sulfate
7. customThe solvent is removed by vacuum evaporation