Flupirtine → Flupirtine maleate

HRID 619677Notes

Reaction equation

[CH3:1][CH2:2][O:3][C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]([NH:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]([F:22])=[CH:20][CH:21]=2)=[N:11][C:12]=1[NH2:13])=[O:5].[C:23]([OH:30])(=[O:29])/[CH:24]=[CH:25]\[C:26]([OH:28])=[O:27]>>[CH3:1][CH2:2][O:3][C:4]([NH:6][C:7]1[CH:8]=[CH:9][C:10]([NH:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]([F:22])=[CH:20][CH:21]=2)=[N:11][C:12]=1[NH2:13])=[O:5].[CH:24](/[C:23]([OH:30])=[O:29])=[CH:25]/[C:26]([OH:28])=[O:27]

Participants

Reactant 2

HCID 53276Flupirtine

HCID 444266Maleic Acid

Product 1

HCID 6435335Flupirtine maleate

Procedure

reaction of the resulting flupirtine base with maleic acid to obtain flupirtine maleate;

Sources & evidence

ORD record: ord-bfe0ef53b92548fba7d137608de77b4d
Source dataset: uspto-grants-1999_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05959115

Reaction notes

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