HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178526622, compound → HCID 178507562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178526622 | HCID 178526622 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178507562 | HCID 178507562 | 53.9% |
Reaction Steps
A solution of 0.2 g of 4-[5-(4-chlorophenyl)-2-(2-chloro-6-nitrophenyl) imidazol-4-yl]pyridine in 20 ml of methanol was hydrogenated in the presence of 0.1 g of 10% palladium/charcoal for 2 hours. The catalyst was filtered off and the solution was evaporated to dryness. Recrystallization from ethyl acetate yielded 0.1 g of 3-chloro-2-[5-(4-chlorophenyl)-4-pyridin-4-yl-imidazol-2-yl]phenylamine, m.p. 220-222° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05959113 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-a4d9b9891bce402d8a359e149cb79435 |
| Source note | uspto-grants-1999_09 |