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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 619681Generated: October 31, 2026

HCID 178526622, compound → HCID 178507562, compound

https://huagongshe.com/reaction/619681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178526622HCID 178526622—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178507562HCID 17850756253.9%

Reaction Steps

A solution of 0.2 g of 4-[5-(4-chlorophenyl)-2-(2-chloro-6-nitrophenyl) imidazol-4-yl]pyridine in 20 ml of methanol was hydrogenated in the presence of 0.1 g of 10% palladium/charcoal for 2 hours. The catalyst was filtered off and the solution was evaporated to dryness. Recrystallization from ethyl acetate yielded 0.1 g of 3-chloro-2-[5-(4-chlorophenyl)-4-pyridin-4-yl-imidazol-2-yl]phenylamine, m.p. 220-222° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05959113
Source datasetuspto-grants-1999_09
ORD IDord-a4d9b9891bce402d8a359e149cb79435
Source noteuspto-grants-1999_09