HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57073292, compound → HCID 57026923, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57073292 | HCID 57073292 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 57026923 | HCID 57026923 | — |
Reaction Steps
(3S, 4S)-3-benzyloxycarbonylamino-4-phenoxy-azetidin-2-one (140 mg, 0.45 mmole) is hydrogenated with 100 mg of 10% palladium on activated carbon in ethyl acetate (20 ml) at 50 psi hydrogen pressure at room temperature for 2 hours. After removal of catalyst by filtration, deprotected (3S, 4S)-3-amino-4-phenoxy-azetidin-2-one in ethyl acetate is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05959123 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-386b5e23b9844fdf97bb4b65651a0957 |
| Source note | uspto-grants-1999_09 |