HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 619724Generated: November 1, 2026
Potassium Carbonate → HCID 21846987, compound
https://huagongshe.com/reaction/619724
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-4-fluorobenzonitrile | HCID 145525 | — |
| Reactant | 5-Isoquinolinethiol | HCID 11051963 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21846987 | HCID 21846987 | 90.3% |
Reaction Steps
According to the method in Example 10, 5-isoquinolinethiol 1.00 g (6.2 mmol), DMF 30 ml, potassium carbonate 1.60 g (11.6 mmol) and 3-chloro-4-fluorobenzonitrile 0.90 g (5.8 mmol) were stirred at 100° C. for 30 minutes, and 3-chloro-4-(5-isoquinolylsulfanyl)benzonitrile 1.55 g (90.3%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05959107 |
|---|
| Source dataset | uspto-grants-1999_09 |
|---|
| ORD ID | ord-14bce37c20ba41918682df03486c906b |
|---|
| Source note | uspto-grants-1999_09 |
|---|
