Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 21846931 | HCID 21846931 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 69949086 | HCID 69949086 | 49% |
Reaction Steps
According to the method in Example 10, a mixture of 5-(5-chloro-2-nitrophenylsulfanyl)isoquinoline 630 mg (2.0 mmol), DMF 5 ml, potassium carbonate 300 mg (2.2 mmol) and imidazole 140 mg (2.1 mmol) was stirred at 140° C. for 3 hours, and 5-[5-(1H-1-imidazolyl)-2-nitrophenylsulfanyl)isoquinoline 340 mg (49.0%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05959107 |
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| Source dataset | uspto-grants-1999_09 |
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| ORD ID | ord-88955723d2b44485bd608d8550ab1d1e |
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| Source note | uspto-grants-1999_09 |
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