反应详情

温度

100 °C

A mixture of 2,7-bis(3,5-dimethylpiperidin-1-ylsulfonyl)-10-methylacridine-9(10H) thione (145 mg, 0.25 mmole), pyridine (5 mL) and dimethylaminopropylamine (0.125 mL, 1 mmole) was stirred at 100° C. for 4 hrs. Solvent was partially evaporated and reaction product was precipitated by addition of methanol. Precipitate was collected by filtration, washed with methanol and dried to give 137 mg (85%) of the title compound. MS 644 (MH+).

1. customSolvent was partially evaporated
2. customreaction product
3. customwas precipitated by addition of methanol
4. filtrationPrecipitate was collected by filtration
5. washwashed with methanol
6. customdried