Triethylamine → N2,N7-bis(4-tert-butylcyclohexyl)-9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonamide

https://huagongshe.com/reaction/61978

Participants

Role	Name	HCID	Charge
Reactant	Triethylamine	HCID 8471	—
Reactant	4-tert-Butylcyclohexylamine	HCID 79396	—
Reactant	9,10-Dioxo-9,10-dihydro-anthracene-2,7-disulfonyl dichloride	HCID 23436603	—
Solvent	Dichloromethane	HCID 6344	—
Product	N2,N7-bis(4-tert-butylcyclohexyl)-9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonamide	HCID 46851178	95%

Reaction Conditions

Temperature	-50 °C

Reaction Steps

Anthraquinone-2,7-disulfonylchloride (10 g, 24.7 mmol)) was dissolved in 200 mL DCM. The solution was cooled to −50° C. To this solution was added 4-tert-butylcyclohexanamine (8.43 g, 54 mmol), followed by triethyl amine (8.6 ml, 61.7 mmol). The reaction mixture was stirred at room temperature for 4 hrs. Solvent was evaporated and the residue was treated with MeOH, filtered off, and dried to obtain 15 g (95%) of the product (1-36) as yellow powder.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09446021B2
Source dataset	uspto-grants-2016_09
ORD ID	ord-e94f88dfad7944568fb1165923aa7c7f
Source note	uspto-grants-2016_09