HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl bromoacetate → HCID 57152511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl bromoacetate | HCID 79177 | — |
| Reactant | HCID 10765378 | HCID 10765378 | — |
| Product | HCID 57152511 | HCID 57152511 | — |
Reaction Steps
The title compound is prepared from 7-methoxynaphthalene-2-sulfonic acid-[1-(2-cyano-pyridin-4-ylmethyl)-2-oxopyrrolidin-3-(S)-yl]amide as described in EXAMPLE 141, Part D using tert-butyl bromoacetate in place of benzyl bromide. The crude product is purified by column chromatography eluting with gradient of 10% EtOAc/CH2Cl2 to 25% EtOAc/CH2Cl2 to afford the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05958918 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-1e0c01e50f32418593bf9412cb050db8 |
| Source note | uspto-grants-1999_09 |