HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Bromomethyl)thiophene → HCID 18392450, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Bromomethyl)thiophene | HCID 520703 | — |
| Reactant | HCID 10765378 | HCID 10765378 | — |
| Product | HCID 18392450 | HCID 18392450 | — |
Reaction Steps
The title compound is prepared from 7-methoxynaphthalene-2-sulfonic acid [1-(2-cyanopyridin-4-ylmethyl)-2-oxopyrrolidin-3-(S)-yl]amide as described in EXAMPLE 141, Part D using 3-bromomethylthiophene in place of benzyl bromide. The crude product is purified by column chromatography eluting with gradient of 10% EtOAc/CH2Cl2 to 25% EtOAc/CH2Cl2 to afford the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05958918 |
| Source dataset | uspto-grants-1999_09 |
| ORD ID | ord-a90f0bbb931940cd9a69a90d18d0575d |
| Source note | uspto-grants-1999_09 |