Toluene → HCID 86742905, compound

Participants

Reaction Steps

A solution of p-pyrrolidinophenylpropargyl alcohol (2C) (5 g) and 4-chloro-1-naphthol (5 g) in toluene (75 cm3) was passed down a column of acidic alumina (100 g), using toluene as eluant. The colourless but heliochromic fraction (which turned blue on exposure to light from a flashgun) was evaporated and the residual solid recrystallised from acetone. The first crop of pure near colourless crystals was the benzochromene (4D; R=Cl).

Provenance & Evidence