HCID 10497335, compound → HCID 14155093, compound

HRID 619930Notes

Reaction equation

HRID 619930 reaction equation
[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][C:19](F)(F)F)[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][CH3:19])[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 10497335HCID 10497335, compound

Product 1

HCID 14155093HCID 14155093, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This material was prepared by heating 2-benzylthio-5-(2,2,2-trifluoroethoxy)-1,2,4-triazolo[1,5-a]pyrimidine in boiling ethanol. The hot mixture was filtered and the filtrate was concentrated. The crude product was recrystallized from isopropanol to yield the desired product as a solid, m.p. 115°-117° C. IR and 1H NMR spectra were in agreement with the assigned structure.

Workup

  1. customThis material was prepared
  2. filtrationThe hot mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customThe crude product was recrystallized from isopropanol

Sources & evidence

ORD record
ord-3de27f26ce4f4b45bcedd35180671138
Source dataset
uspto-grants-1989_04
Patent number
US04818273

Reaction notes

Loading…