Acetyl chloride → 2-Acetoxymethyl-6-chloroaniline

HRID 619965Notes

Reaction equation

HRID 619965 reaction equation
[NH2:1][C:2]1[C:9]([Cl:10])=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].[C:11](Cl)(=[O:13])[CH3:12]>>[C:11]([O:5][CH2:4][C:3]1[CH:6]=[CH:7][CH:8]=[C:9]([Cl:10])[C:2]=1[NH2:1])(=[O:13])[CH3:12]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 14155407(2-Amino-3-chlorophenyl)methanol

Product 1

HCID 141554092-Acetoxymethyl-6-chloroaniline

Procedure

This material was prepared from 2-amino-3-chlorobenzyl alcohol and acetyl chloride by the general procedure outlined in Example 98. The product was isolated as an amber oil and was characterized by IR and 'H NMR spectroscopy and combustion analysis.

Workup

  1. customThe product was isolated as an amber oil

Sources & evidence

ORD record
ord-d5dabadae08f48d4b2440d1dadf6ccc4
Source dataset
uspto-grants-1989_04
Patent number
US04818273

Reaction notes

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