2-(Dimethylamino)ethanol → 2-Hydroxydodecyl-2-hydroxyethyl dimethyl ammonium fluoride

Participants

Reaction Conditions

Reaction Steps

44.57 g of dimethyl ethanolamine (0.5 mole) were diluted with 420.65 g of water, followed by the addition of 19.38 g of an aqueous 41.3% hydrofluoric acid solution (0.4 mole). A clear solution was formed. After the solution had been heated to 95° C., 94.0 g of 1,2-epoxydodecane (0.5 mole) and 3.5 g of a 75% dispersion of distearyl dimethyl ammonium chloride (as phase transfer catalyst) were added, after which the reaction mixture was stirred for 6 hours at 95° C. Finally, another 4.84 g of the 41.3% hydrofluoric acid solution (0.1 mole) were added. A clear yellow solution of the 2-hydroxydodecyl-2-hydroxyethyl dimethyl ammonium fluoride containing 73.1 m vals of quaternary ammonium compound (QUAT) per 100 g of the aqueous solution was obtained.

Provenance & Evidence