Sodium Hydroxide → 4-(2-o-Methoxybenzenesulphonamido-indan-5-yl)-4-oxobutyric acid

HRID 620201Notes

Reaction equation

HRID 620201 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[S:9]([NH:12][CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([C:22](=[O:29])[CH2:23][CH2:24][C:25]([O:27]C)=[O:26])[CH:19]=2)[CH2:14]1)(=[O:11])=[O:10].[OH-].[Na+]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[S:9]([NH:12][CH:13]1[CH2:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([C:22](=[O:29])[CH2:23][CH2:24][C:25]([OH:27])=[O:26])[CH:19]=2)[CH2:14]1)(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 14071513Methyl 4-(2-o-methoxybenzenesulphonamido-indan-5-yl)-4-oxobuty rate

Product 1

HCID 140715144-(2-o-Methoxybenzenesulphonamido-indan-5-yl)-4-oxobutyric acid

Procedure

Prepared analogously to Example 2 from methyl 4-(2-o-methoxybenzenesulphonamido-indan-5-yl)-4-oxobuty rate by hydrolysis with sodium hydroxide.

Sources & evidence

ORD record
ord-161cb8235749432a9777f39de22b2693
Source dataset
uspto-grants-1989_04
Patent number
US04820705

Reaction notes

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