HCID 53850438, compound → HCID 14071531, compound

HRID 620210Notes

Reaction equation

HRID 620210 reaction equation
[C:1]1([S:7]([NH:10][CH:11]2[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([CH:20]([CH3:26])[CH2:21][C:22]([O:24]C)=[O:23])[CH:17]=3)[CH2:12]2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)C>[C:1]1([S:7]([NH:10][CH:11]2[CH2:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([CH:20]([CH3:26])[CH2:21][C:22]([OH:24])=[O:23])[CH:17]=3)[CH2:12]2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 1

HCID 53850438HCID 53850438, compound

Product 1

HCID 14071531HCID 14071531, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.4 g of methyl 3-(2-benzenesulphonamido-indan-5-yl)-butyrate are dissolved in 10 ml of ethanol, 2 ml of 15N sodium hydroxide solution are added, and saponification is carried out by boiling for 1 hour. The mixture is evaporated, the residue is dissolved in water, and the free acid is precipitated as a foamy material by adding hydrochloric acid.

Workup

  1. customThe mixture is evaporated
  2. dissolutionthe residue is dissolved in water
  3. customthe free acid is precipitated as a foamy material
  4. additionby adding hydrochloric acid

Sources & evidence

ORD record
ord-d15aec9014ed499080f046d9325af3cb
Source dataset
uspto-grants-1989_04
Patent number
US04820705

Reaction notes

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