Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → N-phenyl-1H-benzimidazole-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | N-(4-Aminophenyl)propanamide | HCID 314342 | — |
| 생성물 | N-phenyl-1H-benzimidazole-2-carboxamide | HCID 3737768 | — |
반응 단계
14.4 g (0.05 mol) of dibenzimidazo(1,2a,1',2'-d)tetrahydropyrazine-6,13-dione and 30 g (0.18 mol) of 4-propionylaminoaniline are heated under reflux in 70 ml of dry dimethylformamide for 3 hours. After cooling down, about 700 ml of methanol are added. The precipitated solid is filtered off with suction and washed with methanol and dried to leave 20.7 g of the benzimidazole-2-carboxanilide of the formula ##STR93## Melting point 289°-291° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04820757 |
| 출처 데이터셋 | uspto-grants-1989_04 |
| ORD ID | ord-f0c06db7870449daad4b67ed97008eeb |
| 출처 메모 | uspto-grants-1989_04 |