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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 620382Generated: October 29, 2026

Propylene Oxide → HCID 88599654, compound

https://huagongshe.com/reaction/620382

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylene OxideHCID 6378—
Reactant2-Thiopheneacetyl chlorideHCID 162362—
ReactantHCID 88599658HCID 88599658—
SolventDichloromethaneHCID 6344—
ProductHCID 88599654HCID 88599654—

Reaction Steps

p-Nitrobenzyl 7β-amino-3-trifluoromethylsulfonyloxy-1-carba-3-cephem-4-carboxylate is acylated in methylene chloride with 2-thienylacetyl chloride in the presence of propylene oxide and then is deesterified to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04820816
Source datasetuspto-grants-1989_04
ORD IDord-5e9f99d35d124e5eaa25b861bf43857d
Source noteuspto-grants-1989_04