Water → HCID 13206634, compound

Participants

Reaction Steps

24.0 g (237 millimoles) of triethylamine were added dropwise to 15.0 g (72.2 millimoles) of 1,4-dihydro-4-imino-1-phenylpyridazine hydrochloricde and 12.8 g (~98 millimols) of ~80% strength methacryloyl chloride in 200 ml of methylene chloride at room temperature, while stirring. After the addition was complete, stirring was continued for a further 2 hours at room temperature, after which water was added to the reaction mixture. The organic phase was separated off, washed with water and evaporated down. The residue was recrystallized three times from toluene. 3.6 g (21% of theory) of 1,4-dihydro-4-methacryloylimino-1-phenylpyridazine were isolated as yellow crystals of melting point 136° C.

Provenance & Evidence