Benzoyl chloride → HCID 21246384, compound

HRID 620395Notes

Reaction equation

HRID 620395 reaction equation
Cl.[NH:2]=[C:3]1[CH:8]=[CH:7][N:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:5]=[CH:4]1.[C:15]([Cl:23])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[ClH:23].[C:15]([N:2]=[C:3]1[CH:8]=[CH:7][N:6]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[N:5]=[CH:4]1)(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 21246174HCID 21246174, compound

Product 1

HCID 21246384HCID 21246384, compoundYield 37%

Procedure

6.0 (28.9 millimoles) of 1,4-dihydro-4-imino-1-phenylpyridazine hydrochloride in 50 ml of benzoyl chloride were kept at 120° C. for 10 hours, while stirring. The mixture was cooled and then filtered under suction, and the residue was washed with acetone and recrystallized from isopropanol. 3.3 g (37% of theory) of 4-benzoylimino-1,4-dihydro-1-phenylpyridazine hydrochloride were isolated as pale beige crystals of melting point 225°-226° C. (decomposition).

Workup

  1. temperatureThe mixture was cooled
  2. filtrationfiltered under suction
  3. washthe residue was washed with acetone
  4. customrecrystallized from isopropanol

Sources & evidence

ORD record
ord-d5747d1d1f2c4534bc8644cf7ae2ff2f
Source dataset
uspto-grants-1989_04
Patent number
US04820821

Reaction notes

Loading…