Triethylamine → HCID 178485485, compound

Participants

Reaction Steps

5.3 g (52.4 millimoles) of triethylamine were added dropwise to 10.0 g (48.2 millimoles) of 1,4-dihydro-4-imino-1-phenylpyridazine hydrochloride in 25 ml (24.2 g 424 millimoles) of methyl isocyanate at room temperature, while stirring. After the addition was complete, the reaction mixture was diluted with 50 ml of acetone, and stirred for a further 2 hours at room temperature. The product was filtered off under suction, washed with water and acetone, and recrystallized from methanol. 3.0 g (27% of theory) of 1,4-dihydro-4-(methylcarbamyl)-imino-1-phenylpyridazine were isolated as slightly greenish crystals of melting point 205°-206° C.

Provenance & Evidence