Dicyclohexylcarbodiimide → HCID 54368045, compound

Participants

Reaction Steps

17.0 g of 4-(5-decylpyrimidin-2-yl)-benzoic acid (prepared from 4-(5-decylpyrimidin-2-yl)-benzonitrile by saponification) and 11.1 g of 2-fluoro-4-nonylphenol are introduced into 200 ml of dichloromethane and 11.0 g of dicyclohexylcarbodiimide are added. The mixture is stirred for 4 hours at 20°, the precipitated urea is filtered off under suction, and the filtrate is concentrated to a small volume. After adsorptive filtration of the residue over silica gel using ethyl acetate as eluant, 2-fluoro-4-nonylphenyl 4-(5-decylpyrimidin-2-yl)-benzoate is obtained.

Provenance & Evidence