HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pyrenecarboxaldehyde → 2-Isopropyl-2-((1-pyrenylmethyl)amino)-1,3-propanediol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pyrenecarboxaldehyde | HCID 232848 | — |
| Reactant | 2-Amino-2-isopropyl-1,3-propanediol acetate | HCID 14391248 | — |
| Reactant | (+-)(2R*,3S*)-2-((1-Pyrenylmethyl)amino)-2-methyl-1,3-butanediol hydrochloride | HCID 86742932 | — |
| Product | 2-Isopropyl-2-((1-pyrenylmethyl)amino)-1,3-propanediol hydrochloride | HCID 21247340 | — |
Reaction Steps
Using the reductive amination procedure described for 20G, pyrene-1-carbaldehyde (Aldrich) and 2-amino-2-isopropyl-1,3-propanediol acetate (24B) gave 2-isopropyl-2-((1-pyrenylmethyl)amino)-1,3-propanediol hydrochloride mp 244°-245° (dec), (CH3OH/Et2O), (C, H, N, Cl).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04820873 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-306addfc3f9645b6b26bd46dbb57a372 |
| Source note | uspto-grants-1989_04 |