HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 620572Generated: October 31, 2026
HCID 11658997, compound → HCID 15167808, compound
https://huagongshe.com/reaction/620572
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 11658997 | HCID 11658997 | — |
| Reactant | 1H-indole-2-carbonyl Chloride | HCID 11816208 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15167808 | HCID 15167808 | — |
Reaction Steps
1,3-Dihydro-3-(RS)-methylamino-5-phenyl-2H-1,4-benzodiazepin-2-one (130 mg, 0.49 mmol) and indole-2-carbonyl chloride (88 mg, 0.49 mmol) were combined in CH2Cl2 (5 ml) and stirred 2 hours at 25° C. The reaction was concentrated and chromatographed on silica gel (3% MeOH in CH2Cl2) to give the title compound as a white solid from CH2Cl2 : (m.p. 287°-288.5°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04820834 |
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| Source dataset | uspto-grants-1989_04 |
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| ORD ID | ord-4d5b0d99d8404848b4204821ab0d6ab6 |
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| Source note | uspto-grants-1989_04 |
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