HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 15167817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Isovaleryl chloride | HCID 66054 | — |
| Reactant | HCID 7216755 | HCID 7216755 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15167817 | HCID 15167817 | — |
Reaction Steps
Equimolar amounts of 3(S)-amino-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, isovaleryl chloride and triethylamine were mixed in CH2Cl2 at room temperature and stirred 10 minutes. Flash chromatography of the reaction solution on silica gel (10% Et2O in CH2Cl2) provided the title compound as a white foam from Et2O: m.p. 83°-102° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04820834 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-5765642415ae4db4a361f7f142c2e55c |
| Source note | uspto-grants-1989_04 |