HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 14208288, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | HCID 7216755 | HCID 7216755 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14208288 | HCID 14208288 | — |
Reaction Steps
Equimolar amounts of 3(S)-amino-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, trimethylacetylchloride and triethylamine were mixed in CH2Cl2 at room temperature and stirred 10 minutes. Flash chromatography of the reaction solution on silica gel (10% Et2O in CH2Cl2) provided the title compound as a white foam after removal of the solvent: m.p. 85°-94° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04820834 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-e810b2450b68472fb4c20de78538ca67 |
| Source note | uspto-grants-1989_04 |