HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15614792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Methoxyphenyl isocyanate | HCID 87843 | — |
| Reactant | HCID 15167834 | HCID 15167834 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15614792 | HCID 15614792 | — |
Reaction Steps
Equimolar amounts of 3-(R,S)-amino-1,3-dihydro-1-methyl-5-(p-tolyl)-2H-1,4-benzodiazepin-2-one, 3-methoxyphenylisocyanate, and triethylamine were mixed in THF at 0° C. and stirred 20 minutes. Removal of THF in vacuo and crystallization from MeOH gave the title compound: m.p. 240°-242° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04820834 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-75041c967dba4a46879855887af23da0 |
| Source note | uspto-grants-1989_04 |