Acetylacetone → HCID 13772893, compound

HRID 620664Notes

Reaction equation

HRID 620664 reaction equation
Cl.[NH2:2][C:3]1[NH:7][N:6]=[C:5]([NH:8][S:9]([C:12]2[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:13]=2[Cl:19])(=[O:11])=[O:10])[N:4]=1.[CH3:20][C:21](=O)[CH2:22][C:23](=O)[CH3:24]>C(O)(=O)C>[CH3:20][C:21]1[CH:22]=[C:23]([CH3:24])[N:7]2[N:6]=[C:5]([NH:8][S:9]([C:12]3[CH:17]=[C:16]([Cl:18])[CH:15]=[CH:14][C:13]=3[Cl:19])(=[O:10])=[O:11])[N:4]=[C:3]2[N:2]=1

Participants

4

Reactant 2

HCID 31261AcetylacetoneHCID 13772882HCID 13772882, compound

Product 1

HCID 13772893HCID 13772893, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 4.60 g (13.3 mmol) of N-(5-amino-1,2,4-triazol-3-yl)-2,5-dichlorobenzenesulfonamide hydrochloride and 4.0 g (40 mmol) of 2,4-pentanedione in 60 ml of glacial acetic acid was heated at reflux for 4 hours. The reaction mixture was cooled to room temperature and poured into 500 ml of ice water to separate a solid. The solid was collected by filtration and dried to yield 4.53 g (92 percent) of the desired product as a white solid, mp 216.5°-218.5° C.

Workup

  1. temperatureat reflux for 4 hours
  2. customto separate a solid
  3. filtrationThe solid was collected by filtration
  4. customdried

Sources & evidence

ORD record
ord-7cf2bb05b6e14cc898e41da32e128666
Source dataset
uspto-grants-1989_04
Patent number
US04822404

Reaction notes

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