Water → HCID 14500968, compound

Participants

Reaction Steps

To a stirring solution of 2-(1-cyclohexenyl)-3-thiophenesulfonamide (160 mg, 0.657 mmol), and 4-methyl-6-methoxy-2-aminophenoxycarbonyl pyrimidine (180 mg, 0.69 mmol) in 15 ml of acetonitrile was added 1,8-diazabicyclo[5.4.0]undec-7-ene (105 mg, 0.69 mmol). The reaction was stirred overnight, poured into water, acidified with acetic acid and extracted with methylene chloride, dried over magnesium sulfate and concentrated to yield the desired product, 170 mg, m.p. 190°-192° C.

Provenance & Evidence