HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Cbz-2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester → 2-Aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Cbz-2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester | HCID 54425997 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester | HCID 54251388 | — |
Reaction Steps
N-Cbz-2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester is dissolved in CH3OH and hydrogenated over 10% Pd/C in a Paar hydrogenation apparatus. When the reaction is complete the mixture is filtered through Celite and concentrated to yield 2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl ester (600 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822635 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-ff2edcb6052d4937878e24a96d94275c |
| Source note | uspto-grants-1989_04 |