HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(p-Nitrophenoxy)-myristic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 2-(3-nitrophenoxy)tetradecanoate | HCID 14122414 | — |
| Reactant | Ethyl 2-(4-nitrophenoxy)tetradecanoate | HCID 54095639 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(p-Nitrophenoxy)-myristic acid | HCID 3746500 | — |
Reaction Steps
A mixture of 980 g of 2-(p-nitrophenoxy)-myristic acid ethyl ester (synthesized analogously to the 2-(m-nitrophenoxy)-myristic acid ethyl ester of Preparation 1), 375 ml of 10N sodium hydroxide, and 1500 ml of ethanol is stirred for 1 h at room temperature and next acidified with 5000 ml of 1N hydrochloric acid. The resulting precipitate is filtered off, rinsed with water until neutral, and dried. The product (845 g) was recrystallized from n-hexane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04822729 |
| Source dataset | uspto-grants-1989_04 |
| ORD ID | ord-a866a4cb93004cd1b249373b89c0efd7 |
| Source note | uspto-grants-1989_04 |