反应详情

N-Bromosuccinimide (1.1 g, 6.2 mmole) was added portionwise to a solution of 2-methyl-5-nitrobenzofuran (1.0 g, 5.6 mmole) and benzoyl peroxide (50 mg) in carbon tetrachloride (50 ml) and the reaction mixture was heated at reflux temperature for 6 hours in the presence of bright light. The reaction mixture was then cooled, filtered and the filtrate evaporated to dryness. The residue was recrystallised from petroleum ether to give the title compound, yield 0.75 g, m.p. 96°-98°.

1. temperaturethe reaction mixture was heated
2. temperatureat reflux temperature for 6 hours in the presence of bright light
3. temperatureThe reaction mixture was then cooled
4. filtrationfiltered
5. customthe filtrate evaporated to dryness
6. customThe residue was recrystallised from petroleum ether