7-Nitro-3-(6-nitroquinol-2-ylmethyl)-1,2,4,5-tetrahydro-3H-3-benzazepine → 7-amino-3-(6-aminoquinol-2-ylmethyl)-1,2,4,5-tetrahydro-3H-3-benzazepine

HRID 620736Notes

Reaction equation

HRID 620736 reaction equation
[N+:1]([C:4]1[CH:28]=[CH:27][C:7]2[CH2:8][CH2:9][N:10]([CH2:13][C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[C:19]([N+:24]([O-])=O)[CH:20]=4)[N:15]=3)[CH2:11][CH2:12][C:6]=2[CH:5]=1)([O-])=O>C(O)C.[H][H].[Pd]>[NH2:1][C:4]1[CH:28]=[CH:27][C:7]2[CH2:8][CH2:9][N:10]([CH2:13][C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[C:19]([NH2:24])[CH:20]=4)[N:15]=3)[CH2:11][CH2:12][C:6]=2[CH:5]=1

Participants

4

Reactant 1

HCID 212450597-Nitro-3-(6-nitroquinol-2-ylmethyl)-1,2,4,5-tetrahydro-3H-3-benzazepine

Product 1

HCID 212450547-amino-3-(6-aminoquinol-2-ylmethyl)-1,2,4,5-tetrahydro-3H-3-benzazepine

Reagents, catalysts & solvents 2

HCID 178506449HCID 178506449, compoundCatalystHCID 702EthanolSolvent

Procedure

The title compound was prepared similarly to the procedure of Preparation 5 by the hydrogenation of 7-nitro-3-(6-nitroquinol-2-ylmethyl)-1,2,4,5-tetrahydro-3H-3-benzazepine using H2 /Pd/C in ethanol.

Sources & evidence

ORD record
ord-2a12a7d8dccf4af790d947cddcc57da7
Source dataset
uspto-grants-1989_04
Patent number
US04822793

Reaction notes

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